Familial aggregation and heritability of sarcoidosis: a Swedish nested case−control study
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منابع مشابه
Familial aggregation and heritability of pyloric stenosis.
CONTEXT Pyloric stenosis is the most common condition requiring surgery in the first months of life. Case reports have suggested familial aggregation, but to what extent this is caused by common environment or inheritance is unknown. OBJECTIVES To investigate familial aggregation of pyloric stenosis from monozygotic twins to fourth-generation relatives according to sex and maternal and patern...
متن کاملFamilial Aggregation and Heritability of Wuchereria bancrofti Infection.
BACKGROUND The familial recurrence risk of lymphatic filariasis (LF) is unknown. This case study aimed to evaluate the familial susceptibility to infection with Wuchereria bancrofti and to microfilaremia in a village of the Republic of Congo. METHODS The heritability and intrafamilial correlation coefficients were assessed for both W. bancrofti infection and microfilaremia by controlling for ...
متن کاملFamilial Aggregation and Heritability of Congenital Heart Defects.
BACKGROUND Congenital heart defects (CHD) are known to cluster within families, but existing evidence varies for the estimates of familial relative risk (RR). We aimed to examine familial aggregation and heritability of CHD in the general population of Taiwan.Methods and Results:We conducted a population-based family study using the Taiwan National Health Insurance (NHI) research database. Indi...
متن کاملOpioid pharmacogenomics using a twin study paradigm: methods and procedures for determining familial aggregation and heritability.
Opioids are the cornerstone medication for the treatment of moderate to severe pain. However, analgesic opioid requirements and the propensity to suffer from aversive opioid effects, including fatal respiratory depression and addiction, vary widely among patients. The factors underlying the substantial response variance remain largely unknown and need clarification for using opioids more effect...
متن کاملFamilial aggregation and heritability for cardiovascular risk factors: a family based study in Punjab, India
Background: It is well established that the people with elevated SBP, DBP, BMI and WHR are more prone to cardiovascular disease. However, very few studies have focused on the amount of familial aggregation and heritability of these cardiovascular risk factors in Indian population. Therefore, purpose of this study was to investigate the familial aggregation of blood pressures with respect to cer...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2018
ISSN: 0903-1936,1399-3003
DOI: 10.1183/13993003.00385-2018